Influence of creatine supplementation on indicators of glucose metabolism in skeletal muscle of exercised rats

Authors

  • Michel Barbosa Araújo Post-Graduation Program – Graduation in Human Motricity Science – São Paulo State University, UNESP, Department of Physical Education, Rio Claro, SP
  • Leandro Pereira de Moura Post-Graduation Program – Graduation in Human Motricity Science – São Paulo State University, UNESP, Department of Physical Education, Rio Claro, SP
  • Roberto Carlos Vieira Junior Post-Graduation Programs – Bioscience Graduate School of Nutrition, Federal University of Mato Grosso - UFMT, Cuiabá, MT
  • Marcelo Costa Junior Post-Graduation Program – Graduation in Human Motricity Science – São Paulo State University, UNESP, Department of Physical Education, Rio Claro, SP
  • Rodrigo Augusto Dalia Post-Graduation Program – Graduation in Human Motricity Science – São Paulo State University, UNESP, Department of Physical Education, Rio Claro, SP
  • Amanda Christine da Silva Sponton Post-Graduation Program – Graduation in Human Motricity Science – São Paulo State University, UNESP, Department of Physical Education, Rio Claro, SP
  • Carla Ribeiro Post-Graduation Program – Graduation in Human Motricity Science – São Paulo State University, UNESP, Department of Physical Education, Rio Claro, SP
  • Maria Alice Rostom de Mello Post-Graduation Program – Graduation in Human Motricity Science – São Paulo State University, UNESP, Department of Physical Education, Rio Claro, SP

DOI:

https://doi.org/10.5016/6462

Keywords:

Somatic index. Glucose tolerance. Physical activity.

Abstract

Evaluate the effect of creatine supplementation in the diet on indicators of glucose metabolism in skeletal muscle of exercised rats. Forty Wistar adult rats were distributed into four groups for eight weeks: 1) Control: sedentary rats that received balanced diet; 2) Creatine control: sedentary rats that received supplementation of 2% creatine in the balanced diet; 3) Trained: rats that ran on a treadmill at the Maximal Lactate Steady State and received balanced diet; and 4) Supplemented-trained: rats that ran on a treadmill at the Maximal Lactate Steady State and received creatine supplementation (2%) in the balanced diet. The hydric intake increased and the body weight gain decreased in the supplemented-trained group. In the soleus muscle, the glucose oxidation increased in both supplemented groups. The production of lactate and glycemia during glucose tolerance test decreased in the supplemented-trained group. Creatine supplementation in conjunction with exercise training improved muscular glycidic metabolism of rats.

Author Biographies

Michel Barbosa Araújo, Post-Graduation Program – Graduation in Human Motricity Science – São Paulo State University, UNESP, Department of Physical Education, Rio Claro, SP

bachelor's at Physical Education - Full Degree from Universidade de Taubaté - UNITAU (2004), master's at Motricity Sciences (Conceito Capes 6) from Sao Paulo State Universiyt - Rio Claro (2008) and doctorate at Ciências da Motricidade (Conceito Capes 6) from Universidade Estadual Paulista - Rio Claro (2012). Has experience in Fitness, focusing on Fitness, acting on the following subjects: gordura, reabilitação, senescente, glicidico and suplementação.

Leandro Pereira de Moura, Post-Graduation Program – Graduation in Human Motricity Science – São Paulo State University, UNESP, Department of Physical Education, Rio Claro, SP

Acting on the following subjects: diabetic fisilologia, physical activity and hepatic steatosis.

Roberto Carlos Vieira Junior, Post-Graduation Programs – Bioscience Graduate School of Nutrition, Federal University of Mato Grosso - UFMT, Cuiabá, MT

Has experience in the fitness field, acting on the following subjects: Physical fitness, Fitness, exercise, and football.

Marcelo Costa Junior, Post-Graduation Program – Graduation in Human Motricity Science – São Paulo State University, UNESP, Department of Physical Education, Rio Claro, SP

Graduated in Physical Education, Federal University of Uberlândia -UFU. master's at Ciências da Motricidade University Estadual Paulista (UNESP) Rio Claro (CAPES grade 6), in Physiology, Endocrine-Metabolic and Exercise, conducting research in the area of diabetes, hypertension, oxidative stress and exercise physical. Contributes to the study group LAFID (Physiology Laboratory Performance) conducting studies in the area of physical activity and seniors; lactate and resistance exercise; tests of 1-RM and its variables, evaluations, training and futsal.

Rodrigo Augusto Dalia, Post-Graduation Program – Graduation in Human Motricity Science – São Paulo State University, UNESP, Department of Physical Education, Rio Claro, SP

Graduated in Physiotherapy, Methodist University of Piracicaba (2004). Specialist in Sports Physiotherapy and Exercise Physiology. Master of Science program at Motricity Graduate University Estadual Paulista - UNESP (CAPES 6), PhD is currently the same program project involving developing hypertension, cardiac hypertrophy, and mTOR signaling exercise. Contributor and Member Laboratories of Experimental Physiology and Nutrition, Metabolism and Exercise. Have professional experience in the field of Orthopaedic and Sports Physical Therapy, with operations team in professional football. Has experience in the area of ​​physiology, with emphasis on Endocrine Physiology, Hypertension, Diabetes Mellitus, Metabolism and Exercise.

Amanda Christine da Silva Sponton, Post-Graduation Program – Graduation in Human Motricity Science – São Paulo State University, UNESP, Department of Physical Education, Rio Claro, SP

Operates on the following subjects: metabolic syndrome and exercise.

Carla Ribeiro, Post-Graduation Program – Graduation in Human Motricity Science – São Paulo State University, UNESP, Department of Physical Education, Rio Claro, SP

Graduated in Master's Degree in Physical Education from Universidade Estadual Paulista Júlio de Mesquita Filho, UNESP - Purse FAPESP (2005). MSc Paulista State University-UNESP - Purse FAPESP (2008). DPA Sciences Motricity area physiology endocrine-metabolic and exercise - Physical Education Department - Universidade Estadual Paulista-UNESP-Grant FAPESP, proc 09/51538-5). He has experience in Physical Education with an emphasis in Physiology and Endocrine-Metabolic Workout with specificity the contents: Physical training, Metabolic Syndrome, Diabetes Mellitus, Obesity and Metabolism.

Maria Alice Rostom de Mello, Post-Graduation Program – Graduation in Human Motricity Science – São Paulo State University, UNESP, Department of Physical Education, Rio Claro, SP

graduate at Ciencias Biologicas from Universidade de Mogi das Cruzes (1977), master's at Physiology from Universidade de São Paulo (1982) and ph.d. at Physiology from Universidade de São Paulo (1985). Has experience in exercise physiology, focusing on exercise training, acting on the following subjects: metabolism, malnutrition, obesity, metabolic syndrome and diabetes.

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Published

2013-11-19

Issue

V. 19, N. 4 (2013)

Section

Original Articles

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